Article
Female Hormonal Factors and the Risk of Endometrial Cancer in Lynch Syndrome.
JAMA - 7 Jul 2015
Dashti Seyedeh Ghazaleh, Chau Rowena, Ouakrim Driss Ait, Buchanan Daniel D, Clendenning Mark, Young Joanne P, Winship Ingrid M, Arnold Julie, Ahnen Dennis J, Haile Robert W, Casey Graham, Gallinger Steven, Thibodeau Stephen N, Lindor Noralane M, Le Marchand Loïc, Newcomb Polly A, Potter John D, Baron John A, Hopper John L, Jenkins Mark A, Win Aung Ko
Abstract excerpt
IMPORTANCE: Apart from hysterectomy, there is no consensus recommendation for reducing endometrial cancer risk for women with a mismatch repair gene mutation (Lynch syndrome). OBJECTIVE: To investigate the association between hormonal factors and endometrial cancer risk in Lynch syndrome. DESIGN, SETTING, AND PARTICIPANTS: A retrospective cohort study included 1128 women with a mismatch repair gene mutation...
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