Article
Endometrial cancer and Lynch syndrome: clinical and pathologic considerations.
Cancer control : journal of the Moffitt Cancer Center - 1 Jan 2009
Meyer Larissa A, Broaddus Russell R, Lu Karen H
Abstract excerpt
BACKGROUND: Approximately 2% to 5% of endometrial cancers may be due to an inherited susceptibility. Lynch syndrome, also known as hereditary nonpolyposis colorectal cancer (HNPCC) syndrome, an autosomal-dominant inherited cancer susceptibility syndrome caused by a germline mutation in one of the DNA mismatch repair genes, accounts for the majority of inherited cases. Lynch syndrome is associated with early onset...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.