Article
HLA genetic diversity in Hungarians and Hungarian Gypsies: complementary differentiation patterns and demographic signals revealed by HLA-A, -B and -DRB1 in Central Europe.
Tissue antigens - 1 Aug 2015
Inotai D, Szilvasi A, Benko S, Boros-Major A, Illes Z, Bors A, Kiss K P, Rajczy K, Gelle-Hossó A, Buhler S, Nunes J M, Sanchez-Mazas A, Tordai A
Abstract excerpt
Systematic analyses of human leukocyte antigen (HLA) profiles in different populations may increase the efficiency of bone marrow donor selection and help reconstructing human peopling history. We typed HLA-A, -B, and -DRB1 allele groups in two bone marrow donor cohorts of 2402 Hungarians and 186 Hungarian Gypsies and compared them with several Central-European, Spanish Gypsy, and Indian populations. Our results...
Topics
- Adolescent
- Adult
- Alleles
- Bone Marrow Transplantation
- Female
- Founder Effect
- Genetic Drift
- HLA-A Antigens
- HLA-B Antigens
- HLA-DRB1 Chains
- Haplotypes
- Humans
- Hungary