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Allele and extended haplotype polymorphism of HLA-A, -C, -B, -DRB1 and -DQB1 loci in Polish population and genetic affinities to other populations.

Tissue antigens - 1 Mar 2008

Nowak J, Mika-Witkowska R, Polak M, Zajko M, Rogatko-Koroś M, Graczyk-Pol E, Lange A

Abstract excerpt

Human leukocyte antigen (HLA)-A, -C, -B, -DRB1 and -DQB1 alleles were typed in 200 Polish healthy volunteers recruited for stem cell donor registry, using sequence-specific primer (SSP) and direct sequencing-based methods. Enhanced Bayesian approach of expectation maximization algorithm provided by phase platform was used for extended HLA haplotype inferences. The numbers of identified alleles (four-digit...

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PMID: 18179647
DOI: 10.1111/j.1399-0039.2007.00991.x

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