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Article

Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in Chinese women nonsmokers.

PloS one - 1 Jan 2013

Li Cheng, Yin Zhihua, Wu Wei, Li Xuelian, Ren Yangwu, Zhou Baosen

Abstract excerpt

BACKGROUND: The TERT gene is the reverse transcriptase component of telomerase and is essential for the maintenance of telomere DNA length, chromosomal stability and cellular immortality. CLPTM1L gene encodes a protein linked to cisplatin resistance, and it is well conserved and express in various normal or malignant tissues, including lung. METHODS: To test this hypothesis, we genotyped for two significant SNPs...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23738012
DOI: 10.1371/journal.pone.0064988
PMCID: PMC3667812

Genes

TERT

Provenance

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Genetic variations in TERT-CLPTM1L genes and risk of lung cancer in Chinese women nonsmokers.PMID 23738012Read ↗

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