Article
Evaluation of MCF10A as a Reliable Model for Normal Human Mammary Epithelial Cells.
PloS one - 1 Jan 2015
Qu Ying, Han Bingchen, Yu Yi, Yao Weiwu, Bose Shikha, Karlan Beth Y, Giuliano Armando E, Cui Xiaojiang
Abstract excerpt
Breast cancer is the most common cancer in women and a leading cause of cancer-related deaths for women worldwide. Various cell models have been developed to study breast cancer tumorigenesis, metastasis, and drug sensitivity. The MCF10A human mammary epithelial cell line is a widely used in vitro model for studying normal breast cell function and transformation. However, there is limited knowledge about whether...
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