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EMT and tumor metastasis

25 Feb 2015

Abstract excerpt

EMT and MET comprise the processes by which cells transit between epithelial and mesenchymal states, and they play integral roles in both normal development and cancer metastasis. This article reviews these processes and the molecular pathways that contribute to them. First, we compare embryogenesis and development with cancer metastasis. We then discuss the signaling pathways and the differential expression and...

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Identifiers

PMID: 25852822
DOI: 10.1186/s40169-015-0048-3

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