Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic predisposition to left ventricular dysfunction: a multigenic and multi-analytical approach.

Gene - 10 Aug 2014

Mishra Avshesh, Srivastava Anshika, Mittal Tulika, Garg Naveen, Mittal Balraj

Abstract excerpt

BACKGROUND: Left ventricular dysfunction (LVD) is a complex, multifactorial condition, caused by mechanical, neurohormonal, and genetic factors. We have previously observed association of renin-angiotensin-aldosterone system (RAAS), matrix metalloproteinases (MMPs) and inflammatory pathway genes with LVD. Therefore the present study was undertaken to identify the combination of genetic variants and their possible...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Matrix Metalloproteinase 7
Share to Matrix Metalloproteinase 9

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to NF-kappa B p50 Subunit

Share to Polymorphism, Genetic

Share to Receptor, Angiotensin, Type 1

Share to Renin-Angiotensin System

Share to Ventricular Dysfunction, Left

Source

Identifiers

PMID: 24875414
DOI: 10.1016/j.gene.2014.05.060

Genes

NFKB1
CAD
MMP9
MMP7

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic predisposition to left ventricular dysfunction: a multigenic and multi-analytical approach.PMID 24875414Read ↗

Role of inflammatory gene polymorphisms in left ventricular dysfunction (LVD) susceptibility in coronary artery disease (CAD) patients.Semantic proximity Read ↗

Impact of renin-angiotensin-aldosterone system gene polymorphisms on left ventricular dysfunction in coronary artery disease patients.Semantic proximity Read ↗

Role of angiotensin II type I (AT1 A1166C) receptor polymorphism in susceptibility of left ventricular dysfunction.Semantic proximity Read ↗

Association of matrix metalloproteinases (MMP2, MMP7 and MMP9) genetic variants with left ventricular dysfunction in coronary artery disease patients.Semantic proximity Read ↗

Association of natriuretic peptide polymorphisms with left ventricular dysfunction in southern Han Chinese coronary artery disease patients.Semantic proximity Read ↗

Genome-Wide Analysis of Left Ventricular Image-Derived Phenotypes Identifies Fourteen Loci Associated With Cardiac Morphogenesis and Heart Failure DevelopmentSemantic proximity Read ↗

Interleukin-6 receptor rs7529229 T/C polymorphism is associated with left main coronary artery disease phenotype in a Chinese population.Semantic proximity Read ↗

Renin-angiotensin system gene polymorphisms and diastolic heart failure.Semantic proximity Read ↗

Polymorphisms of beta-adrenoceptor and natriuretic peptide receptor genes influence the susceptibility to and the severity of idiopathic dilated cardiomyopathy in a Chinese cohort.Semantic proximity Read ↗

[ACE and AGTR1 genes polymorphisms in left ventricular hypertrophy pathogenesis in humans].Semantic proximity Read ↗

Key genetic variants in the renin-angiotensin system and left ventricular mass in a cohort of Polish patients with heart failure.Semantic proximity Read ↗

Genetic variation associated with ischemic heart failure: a HuGE review and meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.