Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6.

Molecular medicine reports - 1 Oct 2015

Luo Jiashun, Li Hui, Zhang Chunfang

Abstract excerpt

MicroRNA (miR)-7 has been reported to act as a suppressor in several types of cancer, including non-small cell lung cancer (NSCLC). In addition, paired box 6 (Pax6), a highly conserved transcriptional factor, has been implicated in NSCLC. However, the exact role of miR-7, and the association between miR-7 and Pax6 in NSCLC cells remain to be fully elucidated. The present study demonstrated that miR-7 was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Movement
Share to Extracellular Signal-Regulated MAP Kinases
Share to Eye Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homeodomain Proteins

Share to p38 Mitogen-Activated Protein Kinases

Share to Paired Box Transcription Factors

Share to PAX6 Transcription Factor

Share to RNA Interference

Source

Identifiers

PMID: 26135959
DOI: 10.3892/mmr.2015.4032

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6.PMID 26135959Read ↗

KAT8 promotes the resistance of human NSCLC cells to miR-7 intervention via the H4K16/PAX6 axisSemantic proximity Read ↗

PAX6 enhances Nanog expression by inhibiting NOTCH signaling to promote malignant properties in small cell lung cancer cellsSemantic proximity Read ↗

Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancerSemantic proximity Read ↗

Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.Semantic proximity Read ↗

The molecular mechanisms and therapeutic potential of microRNA-7 in cancerSemantic proximity Read ↗

Long Noncoding RNA SNHG6 Functions as an Oncogene in Non-Small Cell Lung Cancer via Modulating ETS1 SignalingSemantic proximity Read ↗

Function of miR-200a in proliferation and apoptosis of non-small cell lung cancer cellsSemantic proximity Read ↗

Expression of CDCA7 Is a Prognostic Biomarker and Potential Therapeutic Target in Non-small Cell Lung Cancer Semantic proximity Read ↗

SMAD‑6, ‑7 and ‑9 are potential molecular biomarkers for the prognosis in human lung cancerSemantic proximity Read ↗

EGFR promotes lung tumorigenesis by activating miR-7 through a Ras/ERK/Myc pathway that targets the Ets2 transcriptional repressor ERF.Semantic proximity Read ↗

miR-4734 Targets BMP7 to Accelerate Non-Small Cell Lung Cancer Progression and Serves as a Poor Prognostic BiomarkerSemantic proximity Read ↗

MicroRNA-567 inhibits cell proliferation and induces cell apoptosis in A549 NSCLC cells by regulating cyclin-dependent kinase 8Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.