Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancer

22 Mar 2018

Abstract excerpt

Lung cancer is the leading cause of cancer deaths. Novel predictive biomarkers are needed to improve treatment selection and more accurate prognostication. PAX6 is a transcription factor with a proposed tumour suppressor function. Immunohistochemical staining was performed on tissue microarrays from 335 non-small cell lung cancer (NSCLC) patients for PAX6. Multivariate analyses of clinico-pathological variables...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Genomics and Diagnostics
Share to Lung Cancer Treatments and Mutations
Share to RNA modifications and cancer

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29568088
DOI: 10.1038/s41598-018-23417-z

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcription factor PAX6 as a novel prognostic factor and putative tumour suppressor in non-small cell lung cancerPMID 29568088Read ↗

PAX6 enhances Nanog expression by inhibiting NOTCH signaling to promote malignant properties in small cell lung cancer cellsSemantic proximity Read ↗

Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancerSemantic proximity Read ↗

Comprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinomaSemantic proximity Read ↗

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6.Semantic proximity Read ↗

Comprehensive analysis of clinical significance and potential molecular mechanism of PAX gene family in lung squamous cell carcinomaSemantic proximity Read ↗

Comprehensive analysis identifies YKT6 as a potential prognostic and diagnostic biomarker in lung adenocarcinomaSemantic proximity Read ↗

Prognostic Significance of Potential Target Networks and P16INK4a In Early Diagnosis of Non-Small Cell Lung CancerSemantic proximity Read ↗

Identification of SRXN1 and KRT6A as Key Genes in Smoking-Related Non-Small-Cell Lung Cancer Through Bioinformatics and Functional AnalysesSemantic proximity Read ↗

Distinct expression and prognostic value of members of SMAD family in non-small cell lung cancer.Semantic proximity Read ↗

CXCL6 promotes non-small cell lung cancer cell survival and metastasis via down-regulation of miR-515-5pSemantic proximity Read ↗

SMAD‑6, ‑7 and ‑9 are potential molecular biomarkers for the prognosis in human lung cancerSemantic proximity Read ↗

KAT8 promotes the resistance of human NSCLC cells to miR-7 intervention via the H4K16/PAX6 axisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.