Article

KAT8 promotes the resistance of human NSCLC cells to miR-7 intervention via the H4K16/PAX6 axis

2022-05-19

Abstract excerpt

<h4>Background: </h4> Accumulating evidence has shown that microRNAs (miRNAs), one of the representative types of noncoding RNAs (ncRNAs), contribute to the development of non-small-cell lung cancer (NSCLC) and act as promising therapeutic targets in NSCLC. However, how to improve the efficiency of miRNA-based gene intervention against NSCLC remains largely unknown. <h4>Methods: </h4> A proliferation assay was use...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2a01d9e1-6c68-588e-9b31-156ca3ace2cf
DOI: 10.21203/rs.3.rs-1663961/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

KAT8 promotes the resistance of human NSCLC cells to miR-7 intervention via the H4K16/PAX6 axisDOI 10.21203/rs.3.rs-1663961/v1Read

MicroRNA-7 inhibits the malignant phenotypes of non‑small cell lung cancer in vitro by targeting Pax6.Semantic proximity Read

PiRNA-Hsap_1847317 may serve as a novel biomarker of PD-1 inhibitor resistance in patients with advanced non-small cell lung cancerSemantic proximity Read

Long non-coding RNA MALAT1 regulates proliferation, apoptosis, migration and invasion via miR-374b-5p/SRSF7 axis in non-small cell lung cancer.Semantic proximity Read

Upregulation of microRNA-483-5p Advances Non-small Cell Lung Cancer (NSCLC) Progression via Stifling HIPK2 ExpressionSemantic proximity Read

LncRNA PKMYT1AR promotes cancer stem cell maintenance in non-small cell lung cancer via activating Wnt signaling pathwaySemantic proximity Read

Exploring the Impact of hsa_circ_0049168 on Non-Small Cell Lung Cancer Proliferation and Apoptosis via the microRNA-370/PIN1 Regulatory NetworkSemantic proximity Read

Long Noncoding RNA DNAH17-AS1 Promotes Tumorigenesis and Metastasis of Non-Small Cell Lung Cancer via Regulating miR-877-5p/CCNA2 PathwaySemantic proximity Read

Exploring the Impact of hsa_circ_0049168 on NSCLC Proliferation and Apoptosis via the miR-370/PIN1 Regulatory NetworkSemantic proximity Read

Pseudogene KRT17P3 Drives Cisplatin Resistance of Human NSCLC Cells by Modulating miR-497-5p/mTORSemantic proximity Read

Long noncoding RNA PCAT6 functions as an oncogene by binding to EZH2 and suppressing LATS2 in non-small-cell lung cancerSemantic proximity Read

M6A associated TSUC7 inhibition contributed to Erlotinib Resistance in Lung Adenocarcinoma through a Notch Signaling Activation Dependent WaySemantic proximity Read

The molecular mechanisms and therapeutic potential of microRNA-7 in cancerSemantic proximity Read