Article
Genetic Basis and Functional Consequences of Differential Expression of the CmeABC Efflux Pump in Campylobacter jejuni Isolates.
PloS one - 1 Jan 2015
Grinnage-Pulley Tara, Zhang Qijing
Abstract excerpt
The CmeABC multidrug efflux transporter of Campylobacter jejuni plays a key role in antimicrobial resistance and is suppressed by CmeR, a transcriptional regulator of the TetR family. Overexpression of CmeABC has been observed in laboratory-generated mutants, but it is unknown if this phenotype occurs naturally in C. jejuni isolates and if it has any functional consequences. To answer these questions, expression...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
