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Article

Dual Repression of the Multidrug Eﬄux Pump CmeABC by CosR and CmeR in Campylobacter jejuni

13 Jul 2016

Abstract excerpt

During transmission and intestinal colonization, Campylobacter jejuni, a major foodborne human pathogen, experiences oxidative stress. CosR, a response regulator in C. jejuni, modulates the oxidative stress response and represses expression of the CmeABC multidrug eﬄux pump. CmeABC, a key component in resistance to toxic compounds including antimicrobials and bile salts, is also under negative regulation by CmeR,...

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Identifiers

PMID: 27468281
DOI: 10.3389/fmicb.2016.01097

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