Article
Correlation between gyrA and CmeR Box Polymorphism and Fluoroquinolone Resistance in Campylobacter jejuni Isolates in China.
Antimicrobial agents and chemotherapy - 1 Jul 2017
Zhang Tengfei, Cheng Yiluo, Luo Qingping, Lu Qin, Dong Jun, Zhang Rongrong, Wen Guoyuan, Wang Honglin, Luo Ling, Wang Hongcai, Liu Guoping, Shao Huabin
Abstract excerpt
Sequence analysis of 79 ciprofloxacin-resistant Campylobacter jejuni isolates collected in China showed resistance-related sequence variations in gyrA and CmeR-Box. All the isolates contain an identical Thr-86-Ile substitution in GyrA. Several novel CmeR-Box variations, including point substitutions, deletion, and insertion, were identified. The point insertion or deletion led to dramatically reduced binding of...
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