Article
Elucidation of Increased Cervical Cancer Risk Due to Polymorphisms in XRCC1 (R399Q and R194W), ERCC5 (D1104H), and NQO1 (P187S).
Reproductive sciences (Thousand Oaks, Calif.) - 1 Apr 2023
Das Agneesh Pratim, Saini Sandeep, Tyagi Shrishty, Chaudhary Nisha, Agarwal Subhash Mohan
Abstract excerpt
Genetic variations like single nucleotide polymorphisms (SNPs) are associated with cervical carcinogenesis. In this study, SNPs have been identified that contribute toward changes in the function and stability of the proteins and show association with cervical cancer. Initially, literature mining identified 114 protein-coding polymorphisms with population-based evidence in cervical cancer. Subsequently, the...
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