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Article

Neisseria gonorrhoeae Modulates Immunity by Polarizing Human Macrophages to a M2 Profile.

PloS one - 1 Jan 2015

Ortiz María Carolina, Lefimil Claudia, Rodas Paula I, Vernal Rolando, Lopez Mercedes, Acuña-Castillo Claudio, Imarai Mónica, Escobar Alejandro

Abstract excerpt

Current data suggest that Neisseria gonorrhoeae is able to suppress the protective immune response at different levels, such as B and T lymphocytes and antigen-presenting cells. The present report is focused on gonococcus evasion mechanism on macrophages (MФ) and its impact in the subsequent immune response. In response to various signals MФ may undergo classical-M1 (M1-MФ) or alternative-M2 (M2-MФ) activation....

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Identifiers

PMID: 26125939
DOI: 10.1371/journal.pone.0130713
PMCID: PMC4488386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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