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Neisseria gonorrhoeae Modulates Iron-Limiting Innate Immune Defenses in Macrophages

28 Jan 2014

Abstract excerpt

Neisseria gonorrhoeae is a strict human pathogen that causes the sexually transmitted infection termed gonorrhea. The gonococcus can survive extracellularly and intracellularly, but in both environments the bacteria must acquire iron from host proteins for survival. However, upon infection the host uses a defensive response by limiting the bioavailability of iron by a number of mechanisms including the enhanced...

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PMID: 24489950
DOI: 10.1371/journal.pone.0087688

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