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Gonococcal PorB: a multifaceted modulator of host immune responses

25 Oct 2023

Abstract excerpt

Neisseria gonorrhoeae is a human-specific pathogen responsible for the sexually transmitted infection, gonorrhoea. N. gonorrhoeae promotes its survival by manipulating both innate and adaptive immune responses. The most abundant gonococcal outer-membrane protein is PorB, an essential porin that facilitates ion exchange. Importantly, gonococcal PorB has several immunomodulatory properties. To subvert the innate...

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PMID: 37891023
DOI: 10.1016/j.tim.2023.10.002

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