Article
Polymorphisms in GSTM1, GSTT1, GSTP1, and GSTM3 genes and breast cancer risk in northeastern Mexico.
Genetics and molecular research : GMR - 11 Jun 2015
Jaramillo-Rangel G, Ortega-Martínez M, Cerda-Flores R M, Barrera-Saldaña H A
Abstract excerpt
Glutathione S-transferases (GSTs) are a family of phase II metabolizing enzymes involved in carcinogen detoxification and the metabolism of various bioactive compounds. Several genes that code for these enzymes are polymorphic in an ethnicity-dependent manner, with particular genotypes previously associated with an increased risk of breast cancer. The purpose of this study was to determine the frequencies of...
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