Article
Lack of BRAF-V600E Mutation in Papillary Tumor of the Pineal Region.
Neurosurgery - 1 Oct 2015
Cimino Patrick J, Gonzalez-Cuyar Luis F, Perry Arie, Dahiya Sonika
Abstract excerpt
BACKGROUND: Papillary tumor of the pineal region (PTPR) is a rare central nervous system tumor with a variably aggressive clinical behavior, corresponding to World Health Organization grade II/III. Very little is known about the genetic mutations comprising PTPR. Recent studies have shown that other papillary tumors harbor BRAF-V600E mutations, namely papillary thyroid carcinoma and papillary craniopharyngioma,...
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