Papillary Tumor of the Pineal Region: A Distinct Molecular Entity.

doi:10.1111/bpa.12282

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity.

Brain pathology (Zurich, Switzerland) - 1 Mar 2016

Heim Stephanie, Sill Martin, Jones David T W, Vasiljevic Alexandre, Jouvet Anne, Fèvre-Montange Michelle, Wesseling Pieter, Beschorner Rudi, Mittelbronn Michel, Kohlhof Patricia, Hovestadt Volker, Johann Pascal, Kool Marcel, Pajtler Kristian W, Korshunov Andrey, Ruland Vincent, Sperveslage Jan, Thomas Christian, Witt Hendrik, von Deimling Andreas, Paulus Werner, Pfister Stefan M, Capper David, Hasselblatt Martin

Abstract excerpt

Papillary tumor of the pineal region (PTPR) is a neuroepithelial brain tumor, which might pose diagnostic difficulties and recurs often. Little is known about underlying molecular alterations. We therefore investigated chromosomal copy number alterations, DNA methylation patterns and mRNA expression profiles in a series of 24 PTPRs. Losses of chromosome 10 were identified in all 13 PTPRs examined. Losses of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chromosome Aberrations

Share to Disease-Free Survival

Share to DNA Methylation

Share to Ependymoma

Share to Neoplasm Recurrence, Local

Share to Pineal Gland

Share to RNA, Messenger

Source

Open in PubMed Open full text

Identifiers

PMID: 26113311
DOI: 10.1111/bpa.12282
PMCID: PMC8029206

Genes

SPDEF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity.PMID 26113311Read ↗

Papillary tumor of the pineal region: analysis of DNA methylation profiles and clinical outcomes in 76 casesSemantic proximity Read ↗

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations.Semantic proximity Read ↗

Microarray Analysis Reveals Differential Gene Expression Patterns in Tumors of the Pineal RegionSemantic proximity Read ↗

PTEN mutations and activation of the PI3K/Akt/mTOR signaling pathway in papillary tumors of the pineal region.Semantic proximity Read ↗

Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus studySemantic proximity Read ↗

Comprehensive profiling of myxopapillary ependymomas identifies a distinct molecular subtype with relapsing diseaseSemantic proximity Read ↗

Recurrent genetic alterations in epigenetically defined pineoblastoma subtypes.Semantic proximity Read ↗

Histopathologic review of pineal parenchymal tumors identifies novel morphologic subtypes and prognostic factors for outcome.Semantic proximity Read ↗

Papillary tumor of the pineal region: a case involving isocitrate dehydrogenase (IDH) genotyping.Semantic proximity Read ↗

TERT promoter mutation and chromosome 6 loss define a high-risk subtype of ependymoma evolving from posterior fossa subependymoma.Semantic proximity Read ↗

Clinical and molecular heterogeneity of pineal parenchymal tumors: a consensus studySemantic proximity Read ↗

Significance of molecular classification of ependymomas: C11orf95-RELA fusion-negative supratentorial ependymomas are a heterogeneous group of tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.