Article
Origin and dynamics of admixture in Brazilians and its effect on the pattern of deleterious mutations.
Proceedings of the National Academy of Sciences of the United States of America - 14 Jul 2015
Kehdy Fernanda S G, Gouveia Mateus H, Machado Moara, Magalhães Wagner C S, Horimoto Andrea R, Horta Bernardo L, Moreira Rennan G, Leal Thiago P, Scliar Marilia O, Soares-Souza Giordano B, Rodrigues-Soares Fernanda, Araújo Gilderlanio S, Zamudio Roxana, Sant Anna Hanaisa P, Santos Hadassa C, Duarte Nubia E, Fiaccone Rosemeire L, Figueiredo Camila A, Silva Thiago M, Costa Gustavo N O, Beleza Sandra, Berg Douglas E, Cabrera Lilia, Debortoli Guilherme, Duarte Denise, Ghirotto Silvia, Gilman Robert H, Gonçalves Vanessa F, Marrero Andrea R, Muniz Yara C, Weissensteiner Hansi, Yeager Meredith, Rodrigues Laura C, Barreto Mauricio L, Lima-Costa M Fernanda, Pereira Alexandre C, Rodrigues Maíra R, Tarazona-Santos Eduardo
Abstract excerpt
While South Americans are underrepresented in human genomic diversity studies, Brazil has been a classical model for population genetics studies on admixture. We present the results of the EPIGEN Brazil Initiative, the most comprehensive up-to-date genomic analysis of any Latin-American population. A population-based genome-wide analysis of 6,487 individuals was performed in the context of worldwide genomic...
Topics
- Black People
- Brazil
- Genetics, Population
- Humans
- Mutation
- White People