Article
Genome-wide patterns of population structure and admixture in West Africans and African Americans.
Proceedings of the National Academy of Sciences of the United States of America - 12 Jan 2010
Bryc Katarzyna, Auton Adam, Nelson Matthew R, Oksenberg Jorge R, Hauser Stephen L, Williams Scott, Froment Alain, Bodo Jean-Marie, Wambebe Charles, Tishkoff Sarah A, Bustamante Carlos D
Abstract excerpt
Quantifying patterns of population structure in Africans and African Americans illuminates the history of human populations and is critical for undertaking medical genomic studies on a global scale. To obtain a fine-scale genome-wide perspective of ancestry, we analyze Affymetrix GeneChip 500K genotype data from African Americans (n = 365) and individuals with ancestry from West Africa (n = 203 from 12...
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