Article
Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions.
Molecular biology and evolution - 1 Mar 2017
Mychaleckyj Josyf C, Havt Alexandre, Nayak Uma, Pinkerton Relana, Farber Emily, Concannon Patrick, Lima Aldo A, Guerrant Richard L
Abstract excerpt
Despite its population, geographic size, and emerging economic importance, disproportionately little genome-scale research exists into genetic factors that predispose Brazilians to disease, or the population genetics of risk. After identification of suitable proxy populations and careful analysis of tri-continental admixture in 1,538 North-Eastern Brazilians to estimate individual ancestry and ancestral allele...
Topics
- Alleles
- Black People
- Brazil
- Ethnicity
- Gene Frequency
- Genetic Association Studies
- Genetic Variation
- Genetics, Population
- Genome, Human
- Genotype
- Humans