Admixture's impact on Brazilian population evolution and health.

doi:10.1126/science.adl3564

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Article

Admixture's impact on Brazilian population evolution and health.

Science (New York, N.Y.) - 15 May 2025

Nunes Kelly, Araújo Castro E Silva Marcos, Rodrigues Maíra R, Lemes Renan Barbosa, Pezo-Valderrama Patricio, Kimura Lilian, de Sena Lucas Schenatto, Krieger José Eduardo, Catoia Varela Margareth, de Azevedo Luiz Otávio, Aranha Camargo Luis Marcelo, Ferreira Ricardo G M, Krieger Henrique, Bortolini Maria Cátira, Mill José Geraldo, Sacuena Putira, Guerreiro João F, de Souza Celia M B, Veronese Francisco V, Vianna Fernanda S L, Comas David, Pereira Alexandre C, Pereira Lygia V, Hünemeier Tábita

Abstract excerpt

Brazil, the largest Latin American country, is underrepresented in genomic research despite boasting the world's largest recently admixed population. In this study, we generated 2723 high-coverage whole-genome sequences from the Brazilian population, including urban, rural, and riverine communities representing diverse ethnic backgrounds. We reveal the impressive genomic diversity of Brazilians, identifying >8...

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PMID: 40373151
DOI: 10.1126/science.adl3564

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