Article
Whole-genome sequencing of 1,171 elderly admixed individuals from São Paulo, Brazil.
Nature communications - 4 Mar 2022
Naslavsky Michel S, Scliar Marilia O, Yamamoto Guilherme L, Wang Jaqueline Yu Ting, Zverinova Stepanka, Karp Tatiana, Nunes Kelly, Ceroni José Ricardo Magliocco, de Carvalho Diego Lima, da Silva Simões Carlos Eduardo, Bozoklian Daniel, Nonaka Ricardo, Dos Santos Brito Silva Nayane, da Silva Souza Andreia, de Souza Andrade Heloísa, Passos Marília Rodrigues Silva, Castro Camila Ferreira Bannwart, Mendes-Junior Celso T, Mercuri Rafael L V, Miller Thiago L A, Buzzo Jose Leonel, Rego Fernanda O, Araújo Nathalia M, Magalhães Wagner C S, Mingroni-Netto Regina Célia, Borda Victor, Guio Heinner, Rojas Carlos P, Sanchez Cesar, Caceres Omar, Dean Michael, Barreto Mauricio L, Lima-Costa Maria Fernanda, Horta Bernardo L, Tarazona-Santos Eduardo, Meyer Diogo, Galante Pedro A F, Guryev Victor, Castelli Erick C, Duarte Yeda A O, Passos-Bueno Maria Rita, Zatz Mayana
Abstract excerpt
As whole-genome sequencing (WGS) becomes the gold standard tool for studying population genomics and medical applications, data on diverse non-European and admixed individuals are still scarce. Here, we present a high-coverage WGS dataset of 1,171 highly admixed elderly Brazilians from a census-based cohort, providing over 76 million variants, of which ~2 million are absent from large public databases. WGS...
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