Article
Identification of Prognostic Groups in High-Grade Serous Ovarian Cancer Treated with Platinum-Taxane Chemotherapy.
Cancer research - 1 Aug 2015
Chen Ping, Huhtinen Kaisa, Kaipio Katja, Mikkonen Piia, Aittomäki Viljami, Lindell Rony, Hynninen Johanna, Auranen Annika, Grénman Seija, Lehtonen Rainer, Carpén Olli, Hautaniemi Sampsa
Abstract excerpt
Disseminated high-grade serous ovarian cancer (HGS-OvCa) is an aggressive disease treated with platinum and taxane combination therapy. While initial response can be favorable, the disease typically relapses and becomes resistant to treatment. As genomic alterations in HGS-OvCa are heterogeneous, identification of clinically meaningful molecular markers for outcome prediction is challenging. We developed a novel...
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