Article
Optimization of Mutation Pressure in Relation to Properties of Protein-Coding Sequences in Bacterial Genomes.
PloS one - 1 Jan 2015
Błażej Paweł, Miasojedow Błażej, Grabińska Małgorzata, Mackiewicz Paweł
Abstract excerpt
Most mutations are deleterious and require energetically costly repairs. Therefore, it seems that any minimization of mutation rate is beneficial. On the other hand, mutations generate genetic diversity indispensable for evolution and adaptation of organisms to changing environmental conditions. Thus, it is expected that a spontaneous mutational pressure should be an optimal compromise between these two extremes....
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