Article
Novel Functions and Regulation of Cryptic Cellobiose Operons in Escherichia coli.
PloS one - 1 Jan 2015
Parisutham Vinuselvi, Lee Sung Kuk
Abstract excerpt
Presence of cellobiose as a sole carbon source induces mutations in the chb and asc operons of Escherichia coli and allows it to grow on cellobiose. We previously engineered these two operons with synthetic constitutive promoters and achieved efficient cellobiose metabolism through adaptive evolution. In this study, we characterized two mutations observed in the efficient cellobiose metabolizing strain:...
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