Article
Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose.
Molecular microbiology - 1 Dec 2007
Kachroo Aashiq H, Kancherla Aswani K, Singh Nongmaithem S, Varshney Umesh, Mahadevan Subramony
Abstract excerpt
Wild-type strains of Escherichia coli are normally unable to metabolize cellobiose. However, cellobiose-positive (Cel(+)) mutants arise upon prolonged incubation on media containing cellobiose as the sole carbon source. We show that the Cel(+) derivatives carry two classes of mutations that act concertedly to alter the regulation of the chb operon involved in the utilization of N,N'-diacetylchitobiose. These...
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