Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivation.

Scientific reports - 29 Jun 2015

Lv Mingyu, Zhang Biao, Shi Ying, Han Zhu, Zhang Yan, Zhou Yulai, Zhang Wenyan, Niu Junqi, Yu Xiao-Fang

Abstract excerpt

BST-2/tetherin is an interferon-inducible antiviral protein that blocks the release of various enveloped viruses, including HIV-1. Hepatitis B virus (HBV), a major cause of liver disease, belongs to the Hepadnaviridae family of enveloped DNA viruses. Whether BST-2 regulates HBV production is largely unknown. In this report, we have demonstrated that HBV particle release is modulated by BST-2 in a cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Compartmentation
Share to GPI-Linked Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepatitis B Surface Antigens

Share to Hepatitis B virus

Share to Hepatocytes

Share to Human Immunodeficiency Virus Proteins

Share to Viral Regulatory and Accessory Proteins

Share to Virion

Source

Open in PubMed Open full text

Identifiers

PMID: 26119070
DOI: 10.1038/srep11736
PMCID: PMC4484258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of BST-2/tetherin-induced hepatitis B virus restriction and hepatocyte-specific BST-2 inactivation.PMID 26119070Read ↗

BST2/Tetherin inhibits hepatitis C virus production in human hepatoma cellsSemantic proximity Read ↗

Antiviral Inhibition of Enveloped Virus Release by Tetherin/BST-2: Action and CounteractionSemantic proximity Read ↗

Antiviral Activity of the Interferon-Induced Cellular Protein BST-2/TetherinSemantic proximity Read ↗

Broad-Spectrum Inhibition of Retroviral and Filoviral Particle Release by TetherinSemantic proximity Read ↗

Tetherin and Its Viral AntagonistsSemantic proximity Read ↗

BST2/Tetherin Inhibition of Alphavirus ExitSemantic proximity Read ↗

Mutation of Glycosylation Sites in BST-2 Leads to Its Accumulation at Intracellular CD63-Positive Vesicles without Affecting Its Antiviral Activity against Multivesicular Body-Targeted HIV-1 and Hepatitis B Virus.Semantic proximity Read ↗

Vpu antagonizes BST-2-mediated restriction of HIV-1 release via beta-TrCP and endo-lysosomal trafficking.Semantic proximity Read ↗

Beyond Tethering the Viral Particles: Immunomodulatory Functions of Tetherin ( BST-2 )Semantic proximity Read ↗

Ebola Virus Glycoprotein Counteracts BST-2/Tetherin Restriction in a Sequence-Independent Manner That Does Not Require Tetherin Surface RemovalSemantic proximity Read ↗

Herpes Simplex Virus 1 Counteracts Tetherin Restriction via Its Virion Host Shutoff ActivitySemantic proximity Read ↗

Virus-Activated Interferon Regulatory Factor 7 Upregulates Expression of the Interferon-Regulated BST2 Gene Independently of Interferon SignalingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.