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Article

Comparison of susceptibility of HIV-1 variants to antiretroviral drugs by genotypic and recombinant virus phenotypic analyses.

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases - 1 Aug 2015

Chang Shuai, Zhuang Daomin, Li Jingyun, Liu Siyang, Li Hanping, Han Jingwan, Li Lin, Liu Yongjian, Bao Zuoyi, Li Tianyi, Song Hongbin, Zhang Wenfu

Abstract excerpt

OBJECTIVE: This study utilized genotypic and in-house recombinant virus phenotypic assays to examine HIV-1 variant susceptibility to antiretroviral (ARV) drugs; comparisons were made between the analyses. METHODS: A nested PCR was employed to amplify the HIV-1 gag-pol gene, which comprised the entire PR gene (codons 1-99) and the former RT gene (codons 1-312). Genetic resistance was determined by submitting the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26117343
DOI: 10.1016/j.ijid.2015.06.011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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