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Application of single-cell genomics in cancer: promise and challenges

25 Jun 2015

Abstract excerpt

Recent advances in single-cell genomics are opening up unprecedented opportunities to transform cancer genomics. While bulk tissue genomic analysis across large populations of tumour cells has provided key insights into cancer biology, this approach does not provide the resolution that is critical for understanding the interaction between different genetic events within the cellular hierarchy of the tumour during...

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PMID: 26113645
DOI: 10.1093/hmg/ddv235

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