Article
Disseminated histiocytoses biomarkers beyond BRAFV600E: frequent expression of PD-L1.
Oncotarget - 14 Aug 2015
Gatalica Zoran, Bilalovic Nurija, Palazzo Juan P, Bender Ryan P, Swensen Jeffrey, Millis Sherri Z, Vranic Semir, Von Hoff Daniel, Arceci Robert J
Abstract excerpt
The histiocytoses are rare tumors characterized by the primary accumulation and tissue infiltration of histiocytes and dendritic cells. Identification of the activating BRAFV600E mutation in Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis (LCH) cases provided the basis for the tre...
Topics
- Adolescent
- Adult
- Aged
- B7-H1 Antigen
- Child
- Child, Preschool
- DNA Mutational Analysis
- Dendritic Cell Sarcoma, Follicular
- Dendritic Cells
- Erdheim-Chester Disease
- Female
- Genetic Markers
- Histiocytes
- Histiocytic Sarcoma
- Histiocytosis, Langerhans-Cell