Article
Histiocytic and Dendritic Cell Sarcomas of Hematopoietic Origin Share Targetable Genomic Alterations Distinct from Follicular Dendritic Cell Sarcoma.
The oncologist - 1 Jul 2021
Massoth Lucas R, Hung Yin P, Ferry Judith A, Hasserjian Robert P, Nardi Valentina, Nielsen G Petur, Sadigh Sam, Venkataraman Vinayak, Selig Martin, Friedmann Alison M, Samore Wesley, Killian Jonathan Keith, Milante Riza, Giessinger Joseph, Foley-Peres Kathleen, Marcus Chelsea, Severson Eric, Duncan Daniel, Sivakumar Smruthy, Ross Jeffrey S, Desphande Vikram, Ramkissoon Shakti H, Vergilio Jo-Anne, Louissaint Abner, Zukerberg Lawrence R, Williams Erik A
Abstract excerpt
BACKGROUND: Histiocytic and dendritic cell neoplasms are a diverse group of tumors arising from monocytic or dendritic cell lineage. Whereas the genomic features for Langerhans cell histiocytosis and Erdheim-Chester disease have been well described, other less common and often aggressive tumors in this broad category remain poorly characterized, and comparison studies across the World Health Organization...
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