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Molecular Pathogenesis of the Histiocytic and Dendritic Cell Neoplasms.

Hematology/oncology clinics of North America - 1 Jun 2025

Durham Benjamin H

Abstract excerpt

The histiocytic and dendritic cell neoplasms encompass a clinically heterogeneous group of disorders leading to tissue damage secondary to the accumulation and infiltration of pathologic cells thought to be derived from the dendritic or monocytic lineages with accompanying inflammation. The pathophysiology of these disorders is poorly understood. Studies over the past 15 y have identified a high-frequency of...

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Identifiers

PMID: 40221268
DOI: 10.1016/j.hoc.2025.03.001

Genes

MAP2K1

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