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Searching for SNPs with cloud computing.

Genome biology - 1 Jan 2009

Langmead Ben, Schatz Michael C, Lin Jimmy, Pop Mihai, Salzberg Steven L

Abstract excerpt

As DNA sequencing outpaces improvements in computer speed, there is a critical need to accelerate tasks like alignment and SNP calling. Crossbow is a cloud-computing software tool that combines the aligner Bowtie and the SNP caller SOAPsnp. Executing in parallel using Hadoop, Crossbow analyzes data comprising 38-fold coverage of the human genome in three hours using a 320-CPU cluster rented from a cloud computing...

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Identifiers

PMID: 19930550
DOI: 10.1186/gb-2009-10-11-r134
PMCID: PMC3091327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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