Article

<i>Celeste</i>: A cloud-based genomics infrastructure with variant-calling pipeline suited for population-scale sequencing projects

2025-05-01

Abstract excerpt

<h4>Background</h4> The All of Us Research Program ( All of Us ) is one of the world’s largest sequencing efforts that will generate genetic data for over one million individuals from diverse backgrounds. This historic megaproject will create novel research platforms that integrate an unprecedented amount of genetic data with longitudinal health information. Here, we describe the design of Celeste , a resilient, o...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 64fb51ff-a8fa-50cf-9c5e-2478470bbf12
DOI: 10.1101/2025.04.29.25326690

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

<i>Celeste</i>: A cloud-based genomics infrastructure with variant-calling pipeline suited for population-scale sequencing projectsDOI 10.1101/2025.04.29.25326690Read

Inexpensive and Highly Reproducible Cloud-Based Variant Calling of 2,535 Human Genomes.Semantic proximity Read

Enabling rapid cloud-based analysis of thousands of human genomes via ButlerSemantic proximity Read

GenomeVIP: a cloud platform for genomic variant discovery and interpretation.Semantic proximity Read

Rainbow: a tool for large-scale whole-genome sequencing data analysis using cloud computing.Semantic proximity Read

Sarek: A portable workflow for whole-genome sequencing analysis of germline and somatic variantsSemantic proximity Read

Scalable and efficient DNA sequencing analysis on different compute infrastructures aiding variant discoverySemantic proximity Read

Accelerating genomic workflows using NVIDIA ParabricksSemantic proximity Read

Rapid NGS Analysis on Google Cloud Platform: performance benchmark and user tutorialSemantic proximity Read

GeMSTONE: Orchestrated Prioritization of Human Germline Mutations in the CloudSemantic proximity Read

VelosGT: Edge-Computing for Human Variant AnalysisSemantic proximity Read

Embarrassingly_FASTA: Enabling Recomputable, Population-Scale Pangenomics by Reducing Commercial Genome Processing Costs from $100 to less than $1Semantic proximity Read

A New Cloud‐Native Tool for Pharmacogenetic AnalysisSemantic proximity Read