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Article

Dissection of a Complex Disease Susceptibility Region Using a Bayesian Stochastic Search Approach to Fine Mapping.

PLoS genetics - 1 Jun 2015

Wallace Chris, Cutler Antony J, Pontikos Nikolas, Pekalski Marcin L, Burren Oliver S, Cooper Jason D, García Arcadio Rubio, Ferreira Ricardo C, Guo Hui, Walker Neil M, Smyth Deborah J, Rich Stephen S, Onengut-Gumuscu Suna, Sawcer Stephen J, Ban Maria, Richardson Sylvia, Todd John A, Wicker Linda S

Abstract excerpt

Identification of candidate causal variants in regions associated with risk of common diseases is complicated by linkage disequilibrium (LD) and multiple association signals. Nonetheless, accurate maps of these variants are needed, both to fully exploit detailed cell specific chromatin annotation data to highlight disease causal mechanisms and cells, and for design of the functional studies that will ultimately...

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Identifiers

PMID: 26106896
DOI: 10.1371/journal.pgen.1005272
PMCID: PMC4481316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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