Article
Epigenetic biomarkers in skin cancer.
Cancer letters - 28 Jan 2014
Greenberg Edward S, Chong Kelly K, Huynh Kelly T, Tanaka Ryo, Hoon Dave S B
Abstract excerpt
Epigenetic aberrations have been associated with cutaneous melanoma tumorigenesis and progression including dysregulated DNA gene promoter region methylation, histone modification, and microRNA. Several of these major epigenetic aberrations have been developed into biomarkers. Epigenetic biomarkers can be detected in tissue and in blood as circulating DNA in melanoma patients. There is strong evidence that...
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