Article
Genome-wide association studies and contribution to cardiovascular physiology.
Physiological genomics - 1 Sept 2015
Munroe Patricia B, Tinker Andrew
Abstract excerpt
The study of family pedigrees with rare monogenic cardiovascular disorders has revealed new molecular players in physiological processes. Genome-wide association studies of complex traits with a heritable component may afford a similar and potentially intellectually richer opportunity. In this review we focus on the interpretation of genetic associations and the issue of causality in relation to known and...
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