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Article

WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.

Human molecular genetics - 15 Sept 2015

Baranowska Körberg Izabella, Hofmeister Wolfgang, Markljung Ellen, Cao Jia, Nilsson Daniel, Ludwig Michael, Draaken Markus, Holmdahl Gundela, Barker Gillian, Reutter Heiko, Vukojević Vladana, Clementson Kockum Christina, Lundin Johanna, Lindstrand Anna, Nordenskjöld Agneta

Abstract excerpt

Bladder exstrophy, a severe congenital urological malformation when a child is born with an open urinary bladder, is the most common form of bladder exstrophy-epispadias complex (BEEC) with an incidence of 1:30,000 children of Caucasian descent. Recent studies suggest that WNT genes may contribute to the etiology of bladder exstrophy. Here, we evaluated WNT-pathway genes in 20 bladder exstrophy patients using...

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Source

Identifiers

PMID: 26105184
DOI: 10.1093/hmg/ddv225

Genes

WNT3
FZD5
LRP1
LRP10
WNT11
WNT16
WNT6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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WNT3 involvement in human bladder exstrophy and cloaca development in zebrafish.PMID 26105184Read ↗

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