Article
Structural insights into key sites of vulnerability on <scp>HIV</scp>‐1 Env and influenza <scp>HA</scp>
10 Oct 2012
Abstract excerpt
Human immunodeficiency virus-1 (HIV-1) envelope protein (Env) and influenza hemagglutinin (HA) are the surface glycoproteins responsible for viral entry into host cells, the first step in the virus life cycle necessary to initiate infection. These glycoproteins exhibit a high degree of sequence variability and glycosylation, which are used as strategies to escape host immune responses. Nonetheless, antibodies...
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