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Article

Metabolic side effects of antipsychotic drug treatment--pharmacological mechanisms.

Pharmacology & therapeutics - 1 Jan 2010

Reynolds Gavin P, Kirk Shona L

Abstract excerpt

Obesity and metabolic syndrome, with increased risk of eventual cardiovascular disease and type II diabetes, are significant problems for patients receiving antipsychotic drugs and are likely contribute to their decreased life expectancy. Several drug-related mechanisms may contribute to these problems, including effects both influencing food intake and on glucose and lipid metabolism. The metabolic consequences...

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PMID: 19931306
DOI: 10.1016/j.pharmthera.2009.10.010

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