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Article

Association study between variants of AMP-activated protein kinase catalytic and regulatory subunit genes with antipsychotic-induced weight gain.

Journal of psychiatric research - 1 Apr 2012

Souza Renan P, Tiwari Arun K, Chowdhury Nabilah I, Ceddia Rolando B, Lieberman Jeffrey A, Meltzer Herbert Y, Kennedy James L, Müller Daniel J

Abstract excerpt

Weight gain and metabolic syndrome are the most common deleterious side effects following treatment with second generation antipsychotic drugs such as clozapine and olanzapine. However, the mechanisms underlying these negative effects of second generation antipsychotic drugs are not fully understood. In this study we investigate whether variants in the genes coding for the α-catalytic (PRKAA1, PRAKAA2) and the β...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22305490
DOI: 10.1016/j.jpsychires.2012.01.010

Genes

PRKAB2
PRKAA1
PRKAA2
PRKAB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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