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Article

Functional Analysis of GLRX5 Mutants Reveals Distinct Functionalities of GLRX5 Protein.

Journal of cellular biochemistry - 1 Jan 2016

Liu Gang, Wang Yongwei, Anderson Gregory J, Camaschella Clara, Chang Yanzhong, Nie Guangjun

Abstract excerpt

Glutaredoxin 5 (GLRX5) is a 156 amino acid mitochondrial protein that plays an essential role in mitochondrial iron-sulfur cluster transfer. Mutations in this protein were reported to result in sideroblastic anemia and variant nonketotic hyperglycinemia in human. Recently, we have characterized a Chinese congenital sideroblastic anemia patient who has two compound heterozygous missense mutations (c. 301 A>C and...

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Identifiers

PMID: 26100117
DOI: 10.1002/jcb.25267

Genes

GLRX5

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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