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Article

Effect of the 5-HTTLPR polymorphism on affective temperament, depression and body mass index in obesity.

Journal of affective disorders - 15 Sept 2015

Borkowska A, Bieliński M, Szczęsny W, Szwed K, Tomaszewska M, Kałwa A, Lesiewska N, Junik R, Gołębiewski M, Sikora M, Tretyn A, Akiskal K, Akiskal H

Abstract excerpt

BACKGROUND AND AIM: Many studies show high prevalence of affective disorders in obese patients. Affective temperament is a subclinical manifestation of such conditions. The 5-HTT gene encoding the serotonin transporter may be involved in both mood and eating dysregulation. The aim of this study was to investigate the influence of a polymorphism in the 5-HTT gene on affective temperament types, depressive symptoms...

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Source

Identifiers

PMID: 26093833
DOI: 10.1016/j.jad.2015.05.061

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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