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Article

Serotonin transporter gene promoter polymorphism affects the severity of binge eating in general population.

Progress in neuro-psychopharmacology & biological psychiatry - 1 Feb 2010

Akkermann Kirsti, Nordquist Niklas, Oreland Lars, Harro Jaanus

Abstract excerpt

OBJECTIVE: The s-allele of the 5-HTTLPR has been suggested to lead to the development of less efficient and less flexible 5-HT system and has been associated to different forms of psychopathology. It has also been shown that alterations in serotonergic activity contribute to the pathophysiology of binge eating but it is not clear which changes in 5-HT function observed in eating disorder patients represent trait...

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Identifiers

PMID: 19853632
DOI: 10.1016/j.pnpbp.2009.10.008

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