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Article

Exonic Re-Sequencing of the Chromosome 2q24.3 Parkinson's Disease Locus.

PloS one - 1 Jan 2015

Labbé Catherine, Ogaki Kotaro, Lorenzo-Betancor Oswaldo, Carrasquillo Minerva M, Heckman Michael G, McCarthy Allan, Soto-Ortolaza Alexandra I, Walton Ronald L, Lynch Timothy, Siuda Joanna, Opala Grzegorz, Krygowska-Wajs Anna, Barcikowska Maria, Czyzewski Krzysztof, Dickson Dennis W, Uitti Ryan J, Wszolek Zbigniew K, Ross Owen A

Abstract excerpt

Genome-wide association studies (GWAS) in Parkinson's disease (PD) have identified over 20 genomic regions associated with disease risk. Many of these loci include several candidate genes making it difficult to pinpoint the causal gene. The locus on chromosome 2q24.3 encompasses three genes: B3GALT1, STK39, and CERS6. In order to identify if the causal variants are simple missense changes, we sequenced all 31...

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Source

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Identifiers

PMID: 26090850
DOI: 10.1371/journal.pone.0128586
PMCID: PMC4474914

Genes

STK39
CERS6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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