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Article

Epstein-Barr virus DNA load in chronic lymphocytic leukemia is an independent predictor of clinical course and survival.

Oncotarget - 30 Jul 2015

Visco Carlo, Falisi Erika, Young Ken H, Pascarella Michela, Perbellini Omar, Carli Giuseppe, Novella Elisabetta, Rossi Davide, Giaretta Ilaria, Cavallini Chiara, Scupoli Maria Teresa, De Rossi Anita, D'Amore Emanuele Stefano Giovanni, Rassu Mario, Gaidano Gianluca, Pizzolo Giovanni, Ambrosetti Achille, Rodeghiero Francesco

Abstract excerpt

The relation between Epstein-Barr virus (EBV) DNA load and clinical course of patients with chronic lymphocytic leukemia (CLL) is unknown. We assessed EBV DNA load by quantitative PCR at CLL presentation in mononuclear cells (MNC) of 220 prospective patients that were enrolled and followed-up in two major Institutions. In 20 patients EBV DNA load was also assessed on plasma samples. Forty-one age-matched healthy...

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Share to Epstein-Barr Virus Infections
Share to Herpesvirus 4, Human

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Host-Pathogen Interactions

Share to Kaplan-Meier Estimate

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Leukocytes, Mononuclear

Share to Outcome Assessment, Health Care

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Source

Open in PubMed Open full text

Identifiers

PMID: 26087198
DOI: 10.18632/oncotarget.4418
PMCID: PMC4621917

Genes

NOTCH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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